Meeting Coverage
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ESC
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RESHAPE-HF2 has provocative implications for a wider pool of TEER candidates
by
Nicole Lou, Senior Staff Writer, MedPage Today
August 31, 2024
LONDON — Despite another positive trial, controversy rages on over transcatheter edge-to-edge repair (TEER or M-TEER) in people with symptomatic heart failure (HF) and functional mitral regurgitation (MR).
All three primary endpoints of RESHAPE-HF2 supported significant clinical benefit to the MitraClip procedure in a population with various stages of MR, predominantly severe, reported Stefan Anker, MD, PhD, of Charité Universitätsmedizin Berlin, in a presentation at the European Society of Cardiology (ESC) meeting:
Composite of first or recurrent hospitalization for HF or cardiovascular death during 24 months: 37.0 vs 58.9 events per 100 person-years (RR 0.64, 95% CI 0.48-0.85) Rate of first or recurrent hospitalization for HF during 24 months: 26.9 vs 46.6 events per 100 person-years (RR 0.59, 95% CI 0.42-0.82) Change from baseline to 12 months on the Kansas City Cardiomyopathy Questionnaire-Overall Summary (KCCQ-OS) scale: increase of 21.6 vs 8.0 points on average (P
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